Too Big to Render
This error message is in reference to the size of the STL file, not the physical dimensions of the part. Your part is probably either very complicated or has an excessive amount of detail, resulting in a large file size. It will still print, however you will not be able to preview it beforehand.
Slice Error Review Settings
Occurs when one or more slicer settings are invalid.
Also a known issue with certain versions of Slic3r.